The 9,11-diketone formed by oxidation of PGE2 or PGD2
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Prostaglandin K2

Item No. 18900

Technical Information
Formal Name
9,11-dioxo-15S-hydroxy-prosta-5Z,13E-dien-1-oic acid
CAS Number
275816-51-8
Synonyms
  • PGK2
Molecular Formula
C20H30O5
Formula Weight
Purity
≥98%
A 1 mg/ml solution in methyl acetate
DMF: >100 mg/mlDMSO: >50 mg/mlEthanol: >75 mg/mlPBS (pH 7.2): >2.7 mg/ml
λmax
245 nm
SMILES
O=C(C1)[C@H](C/C=C\CCCC(O)=O)[C@@H](/C=C/[C@@H](O)CCCCC)C1=O
InChi Code
InChI=1S/C20H30O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,21H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+/m0/s1
InChi Key
LGMXPVXJSFPPTQ-DJUJBXLVSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Prostaglandin K2 (PGK2) is the 9,11-diketone formed by the oxidation of PGE2 or PGD2. Whether this compound exists biologically is uncertain; it is known to be resistant to metabolism by 15-hydroxy PGDH in vitro.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Ohno, H., Morikawa, Y., and Hirata, F. Studies on 15-hydroxyprostaglandin dehydrogenase with various prostaglandin analogues. J. Biochem. 84(6), 1485-1494 (1978).