An intermediate in the biosynthesis of trehalose
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Trehalose 6-phosphate (potassium salt hydrate)

Item No. 18925

Technical Information
Formal Name
α-D-glucopyranosyl α-D-glucopyranoside 6-(dihydrogen phosphate), dipotassium salt, hydrate
Molecular Formula
C12H21O14P • 2K [XH2O]
Formula Weight
Purity
≥95%
A crystalline solid
Water: 50mg/mL
SMILES
OC[C@@H](O1)[C@@H](O)[C@H](O)[C@@H](O)[C@@]1([H])O[C@@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](COP([O-])([O-])=O)O2.[K+].[K+].O
InChi Code
InChI=1S/C12H23O14P.2K.H2O/c13-1-3-5(14)7(16)9(18)11(24-3)26-12-10(19)8(17)6(15)4(25-12)2-23-27(20,21)22;;;/h3-19H,1-2H2,(H2,20,21,22);;;1H2/q;2*+1;/p-2/t3-,4-,5-,6-,7+,8+,9-,10-,11-,12-;;;/m1.../s1
InChi Key
WJAKHYYZIIUNPT-USFWYBQWSA-L
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

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    Product Description

    Trehalose 6-phosphate is an intermediate in the biosynthesis of trehalose. It is generated from UDP-glucose and glucose 6-phosphate by trehalose 6-phosphate synthase (TPS or otsA).1 In plants, changes in trehalose 6-phosphate levels positively correlate with diurnal changes in sucrose and may regulate diverse processes, including starch degradation and flowering.2,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Padilla, L., Krämer, R., Stephanopoulos, G., et alOverproduction of trehalose: Heterologous expression of Escherichia coli trehalose-6-phosphate synthase and trehalose-6-phosphate phosphatase in Corynebacterium glutamicum. Appl. Environ. Microbiol. 70(1), 370-376 (2004).

    2. Lunn, J.E., Delorge, I., Figueroa, C.M., et alTrehalose metabolism in plants. Plant J. 79(4), 544-567 (2014).

    3. Wahl, V., Ponnu, J., Schlereth, A., et alRegulation of flowering by trehalose-6-phosphate signaling in Arabidopsis thaliana. Science 339(6120), 704-707 (2013).