A fungal metabolite
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Fulvic Acid

Item No. 19063

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4,10-dihydro-3,7,8-trihydroxy-3-methyl-10-oxo-1H,3H-pyrano[4,3-b][1]benzopyran-9-carboxylic acid
CAS Number
479-66-3
Molecular Formula
C14H12O8
Formula Weight
308.2
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Chloroform: SolubleMethanol: Soluble
λmax
223, 316 nm
SMILES
OC1=C(O)C=C(OC(CC(O)(C)OC2)=C2C3=O)C3=C1C(O)=O
InChi Code
InChI=1S/C14H12O8/c1-14(20)3-8-5(4-21-14)11(16)9-7(22-8)2-6(15)12(17)10(9)13(18)19/h2,15,17,20H,3-4H2,1H3,(H,18,19)
InChi Key
FCYKAQOGGFGCMD-UHFFFAOYSA-N
Origin
Fungus/Penicillium sp. FKP-0046
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $115

    Add

    5 mg

    $518

    Add
    Product Description

    Fulvic acid is a phenolic acid and fungal metabolite originally isolated from Penicillium.1 Fulvic acids are formed via degradation of organisms and their wastes and are classified as humic substances, which are present in soil and water, can form complexes with metals, and can act as oxidizers or reducers.2,3 Fulvic acid is predicted to inhibit amyloid-β (17-42) (Aβ17-42) dimerization, disrupt preformed Aβ17-42 trimers, and bind to the catalytic site of phosphodiesterase 5A (PDE5A) based on molecular dynamics simulation studies.4,5

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Oxford, A.E., Raistrick, H., and Simonart, P. CXXXIX. Studies in the biochemistry of micro-organisms. XLIV. Fulvic acid, a new crystalline yellow pigment, a metabolic product of P. griseo-fulvum Dierckx, P. flexuosum Dale and P. Brefeldianum Dodge. Biochem J. 29(5), 1102-1115 (1935).

    2. Saar, R.A., and Weber, J.H. Fulvic acid: Modifier of metal-ion chemistry. Environ. Sci. Technol. 16(9), 510A-517A (1982).

    3. Klapper, L., McKnight, D.M., Blunt-Harris, E.L., et al. Fulvic acid oxidation state detection using fluorescence spectroscopy. Environ. Sci. Technol. 36(14), 3170-3175 (2002).

    4. Verma, S., Singh, A., and Mishra, A. The effect of fulvic acid on pre- and postaggregation state of Aβ17-42: Molecular dynamics simulation studies. Biochim. Biophys. Acta 1834(12), 2867-2868 (2013).

    5. Verma, S., Singh, A., and Mishra, A. Molecular insight in to the selective inhibition of Phosphodiesterase 5A by fulvic acid (principal constituent of shilajit): Molecular dynamics simulation evidences. Int. J. Drug Design Discov. 3(4), 879-885 (2012).