A hydrophobic spin label
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Biochemicals
Labeling & Detection
Reactive Probes
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EPR/ESR

12-doxyl Stearic Acid

Item No. 19259

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-(10-carboxydecyl)-2-hexyl-4,4-dimethyl-3-oxazolidinyloxy
CAS Number
29545-47-9
Synonyms
  • 12-DSA
Molecular Formula
C22H42NO4
Formula Weight
384.6
Purity
≥95%
Formulation (Request formulation change)
A 1 mg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 10 mg/mlEthanol: 20 mg/ml
λmax
226 nm
SMILES
[O]N1C(C)(C)COC1(CCCCCC)CCCCCCCCCCC(O)=O
InChi Code
InChI=1S/C22H42NO4/c1-4-5-6-14-17-22(23(26)21(2,3)19-27-22)18-15-12-10-8-7-9-11-13-16-20(24)25/h4-19H2,1-3H3,(H,24,25)
InChi Key
BCSQTDYXKYRTKX-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    500 µg

    $41

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    1 mg

    $75

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    5 mg

    $312

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    10 mg

    $544

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    Product Description

    12-Doxyl stearic acid is a form of stearic acid (Item No. 10011298) that contains a 4,4-dimethyl-3-oxazolinyloxy (DOXYL) group, creating a hydrophobic spin label. It is commonly used to study molecular aspects of membranes and hydrophobic proteins.1,2,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Fournier, T., and Rahim, M.H. Self-aggregation, a new property of cardiac fatty acid-binding protein. Predictable influence on energy production in the heart. The Journal of Biological Chemisty 258(5), 2929-2933 (1983).

    2. Musser, S.M., Larsen, R.W., and Chan, S.I. Fluorescence quenching of reconstituted NCD-4-labeled cytochrome c oxidase complex by DOXYL-stearic acids. Biophys. J. 65(6), 2348-2359 (1993).

    3. Nilsson, U.A., Olsson, L.I., Carlin, G., et al. Inhibition of lipid peroxidation by spin labels. Relationships between structure and function. The Journal of Biological Chemisty 264(19), 11131-11135 (1989).