A thiazide-like diuretic
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Clopamide

Item No. 19356

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
rel-3-(aminosulfonyl)-4-chloro-N-(2R,6S-dimethyl-1-piperidinyl)-abenzamide
CAS Number
636-54-4
Molecular Formula
C14H20ClN3O3S
Formula Weight
345.8
Purity
≥98%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMSO: 50 mMEthanol: 10 mM
SMILES
O=C(NN1[C@@H](CCC[C@@H]1C)C)C2=CC(S(N)(=O)=O)=C(C=C2)Cl
InChi Code
InChI=1S/C14H20ClN3O3S/c1-9-4-3-5-10(2)18(9)17-14(19)11-6-7-12(15)13(8-11)22(16,20)21/h6-10H,3-5H2,1-2H3,(H,17,19)(H2,16,20,21)/t9-,10+
InChi Key
LBXHRAWDUMTPSE-AOOOYVTPSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 mg

    $50

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    Product Description

    Clopamide is a thiazide-like diuretic that inhibits sodium/chloride cotransporters in the proximal convoluted tubule of the kidney, which prevents the reabsorption of sodium and chloride.1,2 This compound is intended for research purposes only.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Odlind, B., and Lönnerholm, G. Renal tubular secretion and effects of chlorothiazide, hydrochlorothiazide and clopamide: A study in the avian kidney. Acta.Pharmacol.Toxicol (Copenh) 51(3), 187-197 (1982).

    2. McNeil, J.J., Conway, E.L., Drummer, O.H., et al. Clopamide: Plasma concentrations and diuretic effect in humans. Clin. Pharmacol. Ther. 42(3), 299-304 (1987).