An active component of the antimycin A complex
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Antimycin A1

Item No. 19433

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2(or 3)-methyl-butanoic acid, (2R,3S,6S,7R,8R)-3-[[3-(formylamino)-2-hydroxybenzoyl]amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl ester
CAS Number
642-15-9
Molecular Formula
C28H40N2O9
Formula Weight
548.6
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: SolubleDMSO: SolubleEthanol: SolubleMethanol: Soluble
λmax
230, 321 nm
SMILES
CC(C)CC(O[C@H]([C@H]1CCCCCC)[C@H](C)OC([C@@H](NC(C2=CC=CC(NC([H])=O)=C2O)=O)[C@@H](C)OC1=O)=O)=O
InChi Code
InChI=1S/C28H40N2O9/c1-6-7-8-9-11-20-25(39-22(32)14-16(2)3)18(5)38-28(36)23(17(4)37-27(20)35)30-26(34)19-12-10-13-21(24(19)33)29-15-31/h10,12-13,15-18,20,23,25,33H,6-9,11,14H2,1-5H3,(H,29,31)(H,30,34)/t17-,18+,20-,23+,25+/m1/s1
InChi Key
UIFFUZWRFRDZJC-SBOOETFBSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    500 µg

    $205

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    2.5 mg

    $871

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    Product Description

    Antimycin A1 is an active component of the antimycin A complex.1,2,3 It inhibits electron transport.1 Antimycin A1 (3.3-160 µM) induces the synthesis of carotenoids in M. marinum.2 It also inhibits ATP-citrate lyase (Ki = 29.5 µM).3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Liu, W.-C., and Strong, F.M. The chemistry of antimycin A. VI. Separation and properties of antimycin A subcomponents. J. Am. Chem. Soc. 81(16), 4387-4390 (1959).

    2. Batra, P.P., Harbin, T.L., Howes, C.D., et al. A study of the relationship of structure and activity of antimycin A in the induction of carotenoid synthesis in Mycobacterium marinum. The Journal of Biological Chemisty 246(23), 7125-7130 (1971).

    3. Barrow, C.J., Oleynek, J.J., Marinelli, V., et al. Antimycins, inhibitors of ATP-citrate lyase, from a Streptomyces sp. J. Antibiot. (Tokyo) 50(9), 729-733 (1997).