A precursor to DAPG
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Monoacetylphloroglucinol (hydrate)

Item No. 19451

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-(2,4,6-trihydroxyphenyl)-ethanone, hydrate
Synonyms
  • MAPG
  • NSC 54927
  • Phloroacetophenone
  • 2',4',6'-Trihydroxyacetophenone
Molecular Formula
C8H8O4 • XH2O
Formula Weight
168.1
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mLDMF:PBS(pH 7.2)(1:1): 0.5 mg/mLDMSO: 15 mg/mLEthanol: 25 mg/mL
λmax
209, 226, 286 nm
SMILES
OC1=C(C(C)=O)C(O)=CC(O)=C1.O
InChi Code
InChI=1S/C8H8O4.H2O/c1-4(9)8-6(11)2-5(10)3-7(8)12;/h2-3,10-12H,1H3;1H2
InChi Key
GDSIBPPJKSBCMF-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 g

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    Product Description

    Monoacetylphloroglucinol (MAPG) is a metabolite produced by fluorescent pseudomonads that is acetylated by MAPG acetyltransferase to form the broad-spectrum antibiotic, 2,4-diacetylphloroglucinol (DAPG; Item No. 16345), which is used in the biocontrol of plant diseases by some Pseudomonas strains.1,2,3 MAPG exhibits a broad range of antibiotic activity with fairly weak potency.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hayashi, A., Saitou, H., Mori, T., et al. Molecular and catalytic properties of monoacetylphloroglucinol acetyltransferase from Pseudomonas sp. YGJ3. Biosci. Biotech. Bioch. 76(3), 559-566 (2012).

    2. Meyer, S.L.F., Halbrendt, J.M., Carta, L.K., et al. Toxicity of 2,4-diacetylphloroglucinol (DAPG) to plant-parasitic and bacterial-feeding nematodes. J. Nematol. 41(4), 274-280 (2009).

    3. Shanahan, P., O'Sullivan, D.J., Simpson, P., et al. Isolation of 2,4-diacetylphloroglucinol froma fluorescent pseudomonad and investigation of physiological parameters influencing its production. Appl. Environ. Microbiol. 58(1), 353-358 (2009).