A metabolite of propofol
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Propofol β-D-Glucuronide

Item No. 19517

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2,6-bis(1-methylethyl)phenylβ-D-glucopyranosiduronic acid
CAS Number
114991-26-3
Molecular Formula
C18H26O7
Formula Weight
354.4
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 30 mg/mlPBS (pH 7.2): 10 mg/ml
λmax
211 nm
SMILES
CC(C)C1=CC=CC(C(C)C)=C1O[C@@H]2O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]2O
InChi Code
InChI=1S/C18H26O7/c1-8(2)10-6-5-7-11(9(3)4)15(10)24-18-14(21)12(19)13(20)16(25-18)17(22)23/h5-9,12-14,16,18-21H,1-4H3,(H,22,23)/t12-,13-,14+,16-,18+/m0/s1
InChi Key
JZSJIASBMOIIKI-RUKPJNHUSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    500 µg

    $36

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    1 mg

    $63

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    5 mg

    $230

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    10 mg

    $436

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    Product Description

    Propofol β-D-glucuronide is a metabolite of the anesthetic and sedative propofol.1 It is formed from propofol from the UDP-glucuronosyltransferase (UGT) isoform UGT1A9.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Chen, A., Zhou, X., Cheng, Y., et al. Design and optimization of the cocktail assay for rapid assessment of the activity of UGT enzymes in human and rat liver microsomes. Toxicol. Lett. 295, 379-389 (2018).