Used in neoglycoprotein preparation
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α-D-Galactopyranosylphenyl isothiocyanate

Item No. 19544

Technical Information
Formal Name
α-D-galactopyranoside, isothiocyanatophenyl
CAS Number
120967-92-2
Molecular Formula
C13H15NO6S
Formula Weight
Purity
≥98%
A crystalline solid
DMF: 30 mg/mLDMF:PBS (pH 7) (1:10): 0.09 mg/mLDMSO: 20 mg/mL
λmax
228, 272, 283 nm
SMILES
S=C=NC(C=C1)=CC=C1O[C@@H]2[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O2
InChi Code
InChI=1S/C13H15NO6S/c15-5-9-10(16)11(17)12(18)13(20-9)19-8-3-1-7(2-4-8)14-6-21/h1-4,9-13,15-18H,5H2/t9-,10+,11+,12-,13+/m1/s1
InChi Key
RWANFUZQWINQBY-SJHCENCUSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    α-D-Galactopyranosylphenyl isothiocyanate is a chemically activated form of galactose that has been used to prepare various neoglycoproteins, which consist of a glycosylated serum albumin substituted with either fluorescein or methotrexate.1 Neoglycoproteins are used to identify the presence and sugar specificity of membrane lectins on the cell surface of mouse L1210 leukemia cells and to study membrane lectin-mediated endocytosis.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Monsigny, M., Roche, A.C., and Midoux, P. Uptake of neoglycoproteins via membrane lectin(s) of L1210 cells evidenced by quantitative flow cytofluorometry and drug targeting. Biol. Cell 51(2), 187-196 (1984).