A fluorogenic substrate for triglyceride lipases and cholinesterase
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Resorufin butyrate

Item No. 19592

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3-oxo-3H-phenoxazin-7-yl-butanoic acid ester
CAS Number
15585-42-9
Molecular Formula
C16H13NO4
Formula Weight
283.3
Purity
≥98%
Emission
580 nm
Excitation
570 nm
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mLDMF:PBS (pH 7.2); (1:7): 0.12 mg/mLDMSO: 5 mg/mLEthanol: 0.1 mg/mL
λmax
214, 247, 355, 442 nm
SMILES
O=C1C=CC2=NC(C=CC(OC(CCC)=O)=C3)=C3OC2=C1
InChi Code
InChI=1S/C16H13NO4/c1-2-3-16(19)20-11-5-7-13-15(9-11)21-14-8-10(18)4-6-12(14)17-13/h4-9H,2-3H2,1H3
InChi Key
RGJTZDRUTUWWTD-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

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    5 mg

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    10 mg

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    25 mg

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    50 mg

    $248

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    Product Description

    Resorufin butyrate is a fluorogenic substrate for triglyceride lipases.1 It is also a substrate for cholinesterase.2 Upon enzymatic cleavage by triglyceride lipases or cholinesterase, resorufin is released and can be used to quantify triglyceride lipase or cholinesterase activity. Resorufin displays excitation/emission maxima of 570/580 nm, respectively.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lam, V., Henault, M., Khougaz, K., et al. Resorufin butyrate as a soluble and monomeric high-throughput substrate for a triglyceride lipase. J. Biomol. Screen. 17(2), 245-251 (2012).

    2. Guilbault, G.G., and Kramer, D.N. Resorufin butyrate and indoxyl acetate as fluorogenic substrates for chloinesterase. Anal. Chem. 37, 120-123 (1965).

    3. Hofmann, J., and Sernetz, M. Immobilized enzyme kinetics analyzed by flow-through microfluorimetry: Resorufin-β-D-galactopyranoside as a new fluorogenic substrate for β-galactosidase. Anal. Chim. Acta 163, 67-72 (1984).