A fluorochrome for labeling antibodies
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Product Categories

Product Type

Biochemicals
Labeling & Detection
Fluorescent Probes

Research Area

Application

Fluorescence

Tetramethylrhodamine isothiocyanate (mixed isomers)

Item No. 19593

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
9-(2-carboxyisothiocyanatophenyl)-3,6-bis(dimethylamino)-xanthylium, inner salt
CAS Number
95197-95-8
Synonyms
  • 5(6)-Tetramethylrhodamine isothiocyanate
  • 5(6)-TRITC
  • TRITC
Molecular Formula
C25H21N3O3S
Formula Weight
443.5
Purity
≥95%
Emission
575 nm
Excitation
552 nm
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 5 mg/mlDMSO: 5 mg/mlDMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
λmax
215, 256, 283, 356, 545 nm
SMILES
[O-]C(C(C=C(N=C=S)C=C1)=C1C2=C3C=CC(N(C)C)=CC3=[O+]C4=C2C=CC(N(C)C)=C4)=O.[O-]C(C(C(N=C=S)=CC=C5)=C5C6=C7C=CC(N(C)C)=CC7=[O+]C8=C6C=CC(N(C)C)=C8)=O
InChi Code
InChI=1S/2C25H21N3O3S/c1-27(2)16-6-9-19-22(12-16)31-23-13-17(28(3)4)7-10-20(23)24(19)18-8-5-15(26-14-32)11-21(18)25(29)30;1-27(2)15-8-10-17-21(12-15)31-22-13-16(28(3)4)9-11-18(22)23(17)19-6-5-7-20(26-14-32)24(19)25(29)30/h2*5-13H,1-4H3
InChi Key
DTICYSNQBDFZSM-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    5 mg

    $120

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    10 mg

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    Product Description

    Tetramethylrhodamine isothiocyanate (TRITC) is an amine-reactive derivative of rhodamine that is used as a fluorescent label for antibodies and other probes (ex/em max = 552/575 nm).1 It consists of a base tetramethylrhodamine molecule functionalized with an isothiocyanate reactive group at one of two hydrogen atoms on the bottom ring of the structure. TRITC is reactive towards primary amine groups on proteins, peptides, and other biomolecules.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Li, B., Oestreich, S., and de Lange, T. Identification of human Rap1: Implications for telomere evolution. Cell 101(5), 471-483 (2000).