An antiproliferative isothiocyanate
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Thienyldecyl isothiocyanate

Item No. 19653

Technical Information
Formal Name
2-(10-isothiocyanatodecyl)-thiophene
CAS Number
288323-41-1
Molecular Formula
C15H23NS2
Formula Weight
Purity
≥98%
A solution in ethanol
DMF: 20 mg/mlDMSO: 20 mg/mlEthanol: 30 mg/ml
λmax
235 nm
SMILES
S=C=NCCCCCCCCCCC1=CC=CS1
InChi Code
InChI=1S/C15H23NS2/c17-14-16-12-8-6-4-2-1-3-5-7-10-15-11-9-13-18-15/h9,11,13H,1-8,10,12H2
InChi Key
QRGUKFSTCYZBKD-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Thienyldecyl isothiocyanate is an analog of thienylbutyl isothiocyanate that, like many isothiocyanates, demonstrates antiproliferative activity against cancer cells presumably by modulation of xenobiotic-metabolizing enzymes, such as by inhibition of cytochrome P450, and/or by induction of phase II detoxifying enzymes.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Yu, R., Mandlekar, S., Harvey, K.J., et alChemopreventive isothiocyanates induce apoptosis and caspase-3-like protease activity. Cancer Res. 58(3), 402-408 (1998).