A fluorescent cholesterol analog
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Dehydroergosterol

Item No. 19709

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
ergosta-5,7,9(11),22E-tetraen-3β-ol
CAS Number
516-85-8
Synonyms
  • DHE
  • 9,11-dehydro Ergosterol
Molecular Formula
C28H42O
Formula Weight
394.6
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 2 mg/mlDMSO: 0.1 mg/mlEthanol: 20 mg/mlEthanol:PBS (pH 7.2)(1:2): 0.3 mg/ml
λmax
311, 324 nm
SMILES
CC(C)[C@@H](C)/C=C/[C@@H](C)[C@@]1([H])CC[C@@]2([H])C3=CC=C4C[C@@H](O)CC[C@]4(C)C3=CC[C@@]21C
InChi Code
InChI=1S/C28H42O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h7-10,14,18-20,22,24-25,29H,11-13,15-17H2,1-6H3/b8-7+/t19-,20+,22-,24+,25-,27-,28+/m0/s1
InChi Key
QSVJYFLQYMVBDR-CMNOFMQQSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    5 mg

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    10 mg

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    25 mg

    $436

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    Product Description

    Dehydroergosterol is a naturally occurring, fluorescent analog of cholesterol (ex/em = 324/375 nm) that mimics the properties of cholesterol in cell membranes.1 It is readily bound by cholesterol-binding proteins and has been used for real-time probing of the sterol environment and to elucidate intracellular sterol trafficking in living organisms.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. McIntosh, A.L., Atshaves, B.P., Huang, H., et al. Fluorescence techniques using dehydroergosterol to study cholesterol trafficking. Lipids 43(12), 1185-1208 (2008).

    Product Citations

    Apostoli, A.J., Skelhorne-Gross, G.E., Rubino, R.E., et al. Loss of PPARcexpression in mammary secretory epithelial cellscreates a pro-breast tumorigenic environment. Int. J. Cancer 134(5), 1055-1066 (2014).