A norepinephrine metabolite
Related Products
Parent Compound(s)
38792Normetanephrine (hydrochloride)
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Product Categories

Product Type

Biochemicals

Research Area

Neuroscience

4-hydroxy-3-Methoxyphenylglycol (piperazine salt)

Item No. 19714

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-(4-hydroxy-3-methoxyphenyl)-1,2-ethanediol compound with piperazine
CAS Number
67423-45-4
Synonyms
  • MHPG piperazine
  • MOPEG piperazine
Molecular Formula
C9H12O4 • 1/2C4H10N2
Formula Weight
227.3
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 25 mg/mLDMSO: 15 mg/mLEthanol: 10 mg/mLPBS (pH 7.2): 1 mg/mL
λmax
229, 279 nm
SMILES
COC1=C(O)C=CC(C(O)CO)=C1.C2NCCNC2
InChi Code
InChI=1S/2C9H12O4.C4H10N2/c2*1-13-9-4-6(8(12)5-10)2-3-7(9)11;1-2-6-4-3-5-1/h2*2-4,8,10-12H,5H2,1H3;5-6H,1-4H2
InChi Key
KCECBJRHWSOTMR-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

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    5 mg

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    10 mg

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    Product Description

    4-hydroxy-3-Methoxyphenylglycol (piperazine salt) is a metabolite of norepinephrine derived in part by deamination of normetanephrine or by O-methylation of dihydroxyphenylglycol after cellular uptake of either intermediate.1 It is released into the blood and cerebrospinal fluid and has been used as a biochemical index of recent sympathetic nervous system activity.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kopin, I.J., Axelrod, J., and Gordon, E. The metabolic fate of H3-epinephrine and C14-metanephrine in the rat. The Journal of Biological Chemisty 236(7), 2109-2136 (1961).

    2. Goldstein, D.S., Eisenhofer, G., and Kopin, I.J. Sources and significance of plasma levels of catechols and their metabolites in humans. J. Pharm. Exp. Ther. 305(3), 800-811 (2003).