A modulator of plant signaling
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Product Categories

Product Type

Biochemicals

Research Area

Plant Biology
Plant Growth Regulators

DFPM

Item No. 19830

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
[5-(3,4-dichlorophenyl)-2-furanyl]-1-piperidinyl-methanethione
CAS Number
301338-95-4
Molecular Formula
C16H15Cl2NOS
Formula Weight
340.3
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 2 mg/mlDMSO: 2 mg/mlDMSO:PBS(pH 7.2) (1:4): 0.2 mg/mlEthanol: 0.14 mg/ml
λmax
236, 317 nm
SMILES
S=C(N1CCCCC1)C2=CC=C(C3=CC(Cl)=C(Cl)C=C3)O2
InChi Code
InChI=1S/C16H15Cl2NOS/c17-12-5-4-11(10-13(12)18)14-6-7-15(20-14)16(21)19-8-2-1-3-9-19/h4-7,10H,1-3,8-9H2
InChi Key
SFXIAQRTVLSMEJ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1 mg

    $43

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    5 mg

    $191

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    10 mg

    $337

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    Product Description

    DFPM is a modulator of plant signaling first demonstrated to down-regulate ABA-dependent gene expression (IC50 = 3 µM) and stomatal closure.1 It stimulates the expression of several plant defense-related genes and blocks signaling triggered by phytoalexin deficient 4 (PAD4).1 DFPM also induces root growth arrest in certain accessions of A. thaliana through the expression of a novel protein that interacts with PAD4.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kim, T.-H., Hauser, F., Ha, T., et al. Chemical genetics reveals negative regulation of abscisic acid signaling by a plant immune response pathway. Curr. Biol. 21(11), 990-997 (2011).

    2. Kim, T.-H., Kunz, H.-H., Bhattacharjee, S., et al. Natural variation in small molecule-induced TIR-NB-LRR signaling induces root growth arrest via EDS1- and PAD4-complexed R protein VICTR in Arabidopsis. Plant Cell 24(12), 5177-5192 (2012).