A steroid sapogenin with diverse actions
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Isomer(s)
36008Yamogenin
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Diosgenin

Item No. 19847

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(3β,25R)-spirost-5-en-3-ol
CAS Number
512-04-9
Synonyms
  • Nitogenin
  • NSC 33396
  • 3β-hydroxy-5-Spirostene
Molecular Formula
C27H42O3
Formula Weight
414.6
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
Chloroform: 30 mg/mLDMF: 1 mg/mL
SMILES
C[C@@]12[C@](C[C@@]3([H])[C@]2([H])[C@H](C)[C@]4(OC[C@H](C)CC4)O3)([H])[C@]5([H])CC=C6C[C@@H](O)CC[C@]6(C)[C@@]5([H])CC1
InChi Code
InChI=1S/C27H42O3/c1-16-7-12-27(29-15-16)17(2)24-23(30-27)14-22-20-6-5-18-13-19(28)8-10-25(18,3)21(20)9-11-26(22,24)4/h5,16-17,19-24,28H,6-15H2,1-4H3/t16-,17+,19+,20-,21+,22+,23+,24+,25+,26+,27-/m1/s1
InChi Key
WQLVFSAGQJTQCK-VKROHFNGSA-N
Shipping & Storage Information
Storage
Room temperature
Shipping
Room temperature in continental US; may vary elsewhere
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    5 g

    $41

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    10 g

    $72

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    25 g

    $128

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    100 g

    $235

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    Product Description

    Diosgenin is a natural steroid sapogenin that has diverse biochemical and physiological actions. It has antioxidant and anti-inflammatory activities, is protective against metabolic and cardiovascular diseases, and can have immunomodulatory and estrogenic effects.1,2,3,4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lee, K.J., Oh, Y.C., Cho, W.K., et al. Antioxidant and anti-inflammatory activity determination of one hundred kinds of pure chemical compounds using offline and online screening HPLC assay. Evid. Based Complement. Alternat. Med. 165457 (2015).

    2. Sung, B., Prasad, S., Yadav, V.R., et al. Cancer cell signaling pathways targeted by spice-derived nutraceuticals. Nutr. Cancer 64(2), 173-197 (2012).

    3. Chen, Y., Tang, Y.M., Yu, S.L., et al. Advances in the pharmacological activities and mechanisms of diosgenin. Chin. J. Nat. Med. 13(8), 578-587 (2015).

    4. Fuller, S., and Stephens, J.S. Diosgenin, 4-hydroxyisoleucine, and fiber from fenugreek: Mechanisms of actions and potential effects on metabolic syndrome. Adv. Nutr. 6(2), 189-197 (2015).