A fungal sterol
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Ergosterol

Item No. 19850

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(3β,22E)-ergosta-5,7,22-trien-3-ol
CAS Number
57-87-4
Synonyms
  • Provitamin D2
Molecular Formula
C28H44O
Formula Weight
396.7
Purity
≥85%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 2 mg/mlDMSO: 0.1 mg/mlEthanol: 0.5 mg/mlEthanol:PBS (pH 7.2) (1:2): 0.3 mg/ml
λmax
271, 282, 293 nm
SMILES
CC(C)[C@@H](C)/C=C/[C@@H](C)[C@@]1([H])CC[C@@]2([H])C3=CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C
InChi Code
InChI=1S/C28H44O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h7-10,18-20,22,24-26,29H,11-17H2,1-6H3/b8-7+/t19-,20+,22-,24+,25-,26-,27-,28+/m0/s1
InChi Key
DNVPQKQSNYMLRS-APGDWVJJSA-N
Origin
Plant/Bagasse fermentation
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 g

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    Product Description

    Ergosterol is a sterol that is found predominantly in membranes of fungi. It is converted into vitamin D2 (Item No. 11791) by ultraviolet light.1 Ergosterol and its biosynthetic pathway are significant targets for some fungicides.2,3,4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Bikle, D.D. Vitamin D metabolism, mechanism of action, and clinical applications. Chem. Biol. 21(3), 319-329 (2014).

    2. Ogita, A., Fujita, K.i., and Tanaka, T. Enhancing effects on vacuole-targeting fungicidal activity of amphotericin B. Front. Microbiol. 3, 100 (2012).

    3. Fromtling, R.A. Overview of medically important antifungal azole derivatives. Clin. Microbiol. Rev. 1(2), 187-217 (1988).

    4. Carillo-Muñoz, A.J., Giusiano, G., Ezkurra, P.A., et al. Antifungal agents: mode of action in yeast cells. Rev.Esp.Quimioter. 19(2), 130-139 (2006).