A metabolite of 7-hydroxy coumarin
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7-hydroxy Coumarin Glucuronide (sodium salt)

Item No. 19882

Technical Information
Formal Name
2-oxo-2H-1-benzopyran-7-yl-β-D-glucopyranosiduronic acid, monosodium salt
CAS Number
168286-98-4
Molecular Formula
C15H13O9 • Na
Formula Weight
Purity
≥95%
A crystalline solid
DMF: 14 mg/mlDMSO: 16 mg/mlEthanol: 0.2 mg/mlPBS (pH 7.2): 5 mg/ml
λmax
316 nm
SMILES
O=C1C=CC2=CC=C(O[C@H]3[C@H](O)[C@@H](O)[C@H](O)[C@@H](C([O-])=O)O3)C=C2O1.[Na+]
InChi Code
InChI=1S/C15H14O9.Na/c16-9-4-2-6-1-3-7(5-8(6)23-9)22-15-12(19)10(17)11(18)13(24-15)14(20)21;/h1-5,10-13,15,17-19H,(H,20,21);/q;+1/p-1/t10-,11-,12+,13-,15+;/m0./s1
InChi Key
SKHLGBDGEPDEME-KSOKONAESA-M
Origin
Synthetic
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    7-hydroxy Coumarin glucuronide is a benzopyrone and a metabolite of 7-hydroxy coumarin.1 It is formed from 7-hydroxy coumarin by the UDP-glucuronosyltransferase (UGT) isoform UGT1A1.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Negoro, R., Tasaka, M., Deguchi, S., et alGeneration of HepG2 cells with high expression of multiple drug-metabolizing enzymes for drug discovery research using a PITCh system. Cells 11(10), 1677 (2022).

    Product Citations

    Negoro, R., Tasaka, M., Deguchi, S., et alGeneration of HepG2 cells with high expression of multiple drug-metabolizing enzymes for drug discovery research using a PITCh system. Cells 11(10), 1677 (2022).