An Analytical Reference Standard
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Enantiomer(s)
90086HU-308
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HU-433

Item No. 20032

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(1R,4R,5R)-4-[4-(1,1-dimethylheptyl)-2,6-dimethoxyphenyl]-6,6-dimethyl-bicyclo[3.1.1]hept-2-ene-2-methanol
CAS Number
1220887-84-2
Molecular Formula
C27H42O3
Formula Weight
414.6
Purity
≥98%
Formulation (Request formulation change)
A 10 mg/ml solution in methyl acetate
Solubility(Learn about Variance in Solubility)
Methyl Acetate: Soluble: ≥10 mg/ml
SMILES
CCCCCCC(C)(C)C1=CC(OC)=C(C(OC)=C1)[C@H]2[C@@H]3C(C)(C)[C@@H](C3)C(CO)=C2
InChi Code
InChI=1S/C27H42O3/c1-8-9-10-11-12-26(2,3)19-14-23(29-6)25(24(15-19)30-7)20-13-18(17-28)21-16-22(20)27(21,4)5/h13-15,20-22,28H,8-12,16-17H2,1-7H3/t20-,21+,22-/m1/s1
InChi Key
CFMRIVODIXTERW-BHIFYINESA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    HU-433 (Item No. 20032) is an analytical reference standard categorized as a synthetic cannabinoid.1,2 This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Smoum, R., Baraghithy, S., Chourasia, M., et al. CB2 cannabinoid receptor agonist enantiomers HU-433 and HU-308: An inverse relationship between binding affinity and biological potency. Proc. Natl. Acad. Sci. USA 112(28), 8774-8779 (2015).

    2. Young, A.P., Szczesniak, A.M., Hsu, K., et al. Enantiomeric agonists of the type 2 cannabinoid receptor reduce retinal damage during proliferative vitreoretinopathy and inhibit hyperactive microglia in vitro. ACS Pharmacol. Transl. Sci. 7(5), 1348-1363 (2024).