Fluorescent Thioredoxin Activity Assay Kit | Cayman Chemical
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Fluorescent Thioredoxin Activity Assay Kit

Item № 20039
SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     96 wells $375.00 0.00

Pricing updated 2018-11-15. Prices are subject to change without notice.

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Description
Features
  • Convenient 96-well plate format
  • Measure Trx activity in cell lysates and tissue homogenates
  • Active TrxR and human Trx1 provided with kit
  • Fluorescein-labeled insulin used as substrate - excitation at 480 nm and emission at 520 nm
Synonyms
  • Trx

The thioredoxin system is the major protein disulfide reductase in cells and comprises thioredoxin, thioredoxin reductase and NADPH. Thioredoxin systems are ubiquitous and are critical for cell viability, proliferation, activation of transcription factors, and control of intracellular redox states. The activity of the thioredoxin system has been reported to be disrupted in various physiological disorders such as HIV infection, Alzheimer's disease, and diverse types of cancer and is therefore useful as a biological marker for several diseases. [IMCO Catalog FkTRX-04]

Needed but not supplied: Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.

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Technical Information
Synonyms
  • Trx

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 1 year
Downloads & Resources
Product Downloads

Download Kit Booklet

Download free InChI Key generation software

Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

Get Batch-Specific Data and Documents by Batch Number

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data pack, and GC-MS data.

References & Product Citations
Product Citations

Anderson, K.E., To, M., Olzmann, J.A., et al. Chemoproteomics-enabled covalent ligand screening reveals a thioredoxin-caspase 3 interaction disruptor that impairs breast cancer pathogenicity ACS Chem Biol. (2017).

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