An N-acyl amide
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N-Palmitoyl Phenylalanine

Item No. 20066

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-(1-oxohexadecyl)-L-phenylalanine
CAS Number
37571-96-3
Synonyms
  • N-Hexadecanoyl Phenylalanine
Molecular Formula
C25H41NO3
Formula Weight
403.6
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
Ethanol: Sparingly soluble: 1-10 mg/ml
SMILES
CCCCCCCCCCCCCCCC(N[C@@H](CC1=CC=CC=C1)C(O)=O)=O
InChi Code
InChI=1S/C25H41NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-17-20-24(27)26-23(25(28)29)21-22-18-15-14-16-19-22/h14-16,18-19,23H,2-13,17,20-21H2,1H3,(H,26,27)(H,28,29)/t23-/m0/s1
InChi Key
BAHIJPSQSKWCJX-QHCPKHFHSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 mg

    $186

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    1 g

    $242

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    Product Description

    N-Palmitoyl phenylalanine is an N-acyl amide that contains the long-chain saturated fatty acid palmitic acid (Item No. 10006627) conjugated via an amide bond to the essential amino acid L-phenylalanine (Item No. 31498). It inhibits pre-mRNA splicing in HeLa cell nuclear lysates (IC50 = ~150 µM) but has no splicing activity in intact HeLa cells.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Effenberger, K.A., James, R.C., Urabe, V.K., et al. The natural product N-palmitoyl-L-leucine selectively inhibits late assembly of human spliceosomes. The Journal of Biological Chemisty 290(46), 27524-27531 (2015).