An Analytical Reference Standard
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Certified Reference Material(s)
39570Ibogaine (hydrochloride) (CRM)
Metabolite(s)
40090Noribogaine (hydrochloride)
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Ibogaine (hydrochloride)

Item No. 20083

Restricted Product (Schedule I)
Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • NSC 29847
Technical Information
Formal Name
12-methoxy-ibogamine, monohydrochloride
CAS Number
5934-55-4
Molecular Formula
C20H26N2O • HCl
Formula Weight
346.9
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 0.5 mg/mlDMSO: 0.5 mg/mlEthanol: 0.5 mg/mlMethanol: 1 mg/mlPBS (pH 7.2): 0.1 mg/ml
λmax
210, 278 nm
SMILES
COC(C=C1)=CC2=C1NC3=C2CC[N@@](C4)[C@]5([H])[C@@]3([H])C[C@H]4C[C@@H]5CC.Cl
InChi Code
InChI=1S/C20H26N2O.ClH/c1-3-13-8-12-9-17-19-15(6-7-22(11-12)20(13)17)16-10-14(23-2)4-5-18(16)21-19;/h4-5,10,12-13,17,20-21H,3,6-9,11H2,1-2H3;1H/t12-,13+,17+,20+;/m1./s1
InChi Key
IKJFDJLQPHDRTD-ISYVNWANSA-N
Regulatory Information
DEA Schedule
I
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Ibogaine (hydrochloride) (Item No. 20083) is an analytical reference standard categorized as an iboga alkaloid.1 Ibogaine induces the head-twitch response (HTR), indicating hallucinogenic potential, and anxiety-like behavior in mice.1,2 It decreases self-administration of morphine (Item Nos. ISO60147 | 15464 | 25955) and induces tremors in rats.3 Ibogaine use has been associated with fatalities.4 Ibogaine is regulated as a Schedule I compound in the United States. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Cameron, L.P., Tombari, R.J., Lu, J., et al. A non-hallucinogenic psychedelic analogue with therapeutic potential. Nature 589(7842), 474-479 (2021).

    2. Popik, P., and Wróbel, M. Anxiogenic action of ibogaine. The Alkaloids 227-233 (2001).

    3. Glick, S.D., Rossman, K., Steindorf, S., et al. Effects and aftereffects of ibogaine on morphine self-administration in rats. Eur. J. Pharmacol. 195(3), 341-345 (1991).

    4. Alper, K.R., Stajić, M., and Gill, J.R. Fatalities temporally associated with the ingestion of ibogaine. J. Forensic Sci. 57(2), 398-412 (2012).