An esterized fatty acid involved in quorum sensing
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3-hydroxy Palmitic Acid methyl ester

Item No. 20108

Technical Information
Formal Name
3-hydroxy-hexadecanoic acid, methyl ester
CAS Number
51883-36-4
Synonyms
  • 3-hydroxy PAME
  • 3-hydroxy PA methyl ester
  • SFE 17:0;O
Molecular Formula
C17H34O3
Formula Weight
Purity
≥98%
Formulation
A crystalline solid
Ethanol: 0.5 mg/mLEthanol:PBS(pH 7.2) (1:1): 0.5 mg/mL
λmax
209 nm
SMILES
O=C(CC(O)CCCCCCCCCCCCC)OC
InChi Code
InChI=1S/C17H34O3/c1-3-4-5-6-7-8-9-10-11-12-13-14-16(18)15-17(19)20-2/h16,18H,3-15H2,1-2H3
InChi Key
YBTWUESFQWFDMR-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    3-hydroxy Palmitic acid methyl ester (3-hydroxy PAME) is an esterized long-chain fatty acid involved in quorum sensing in R. solanacearum, a bacteria that causes lethal wilting in plants.1 3-hydroxy-PAME (175 nM) increases levels of PhcA-regulated virulence factors, greater than 20-, 30-, and 25-fold for EPS I, EGL, and PME, respectively, in the AW1-83 strain of R. solanacearum.2 [Matreya, LLC. Catalog No. 1740]

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Archari, G.A., and Ramesh, R. Characterization of bacteria degrading 3-hydroxy palmitic acid methyl ester (3OH-PAME), a quorum sensing molecule of Ralstonia solanacearum. Lett. Appl. Microbiol. 60(5), 447-455 (2015).

    2. Flavier, A., Clough, S.J., Schell, M.A., et alIdentification of 3-hydroxypalmitic acid methyl ester as a novel autoregulator controlling virulence in Ralstonia solanacearum. Mol. Microbiol. 26(2), 251-259 (1997).