An antibiotic of the lincosamide class
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Pirlimycin

Item No. 20138

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-4-ethyl-2-piperidinyl]carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside
CAS Number
79548-73-5
Synonyms
  • U-57930E
Molecular Formula
C17H31ClN2O5S
Formula Weight
411.0
Purity
≥99%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: SolubleDMSO: SolubleEthanol: SolubleMethanol: SolubleWater: Soluble
SMILES
CC[C@@H]1CCN[C@H](C(N[C@@]([C@@H](Cl)C)([H])[C@@]2([H])O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O)=O)C1
InChi Code
InChI=1S/C17H31ClN2O5S/c1-4-9-5-6-19-10(7-9)16(24)20-11(8(2)18)15-13(22)12(21)14(23)17(25-15)26-3/h8-15,17,19,21-23H,4-7H2,1-3H3,(H,20,24)/t8-,9+,10-,11+,12-,13+,14+,15+,17+/m0/s1
InChi Key
HBJOXQRURQPDEX-MHXMMLMNSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $214

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    5 mg

    $851

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    Product Description

    Pirlimycin is a lincosamide antibiotic that is effective against Gram-positive bacteria, including Staphylococcus, Streptococcus, Bacteroides, and Plasmodium.1 It inhibits bacterial protein synthesis by binding to the 50S subunit of the ribosome. Pirlimycin has been used by veterinarians in the treatment of mastitis in dairy cattle.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Birkenmeyer, R.D., Kroll, S.J., Lewis, C., et al. Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. J. Med. Chem 27(2), 216-223 (1984).

    2. Lindeman, C.J., Portis, E., Johansen, L., et al. Susceptibility to antimicrobial agents among bovine mastitis pathogens isolated from North American dairy cattle, 2002-2010. J. Vet. Diagn. Invest. 25(5), 581-591 (2013).