A natural analog of glutamate
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L-Quisqualic Acid

Item No. 20211

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
αS-amino-3,5-dioxo-1,2,4-oxadiazolidine-2-propanoic acid
CAS Number
52809-07-1
Molecular Formula
C5H7N3O5
Formula Weight
189.1
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Water: 25 mM
SMILES
O=C1NC(N(C[C@@H](C(O)=O)N)O1)=O
InChi Code
InChI=1S/C5H7N3O5/c6-2(3(9)10)1-8-4(11)7-5(12)13-8/h2H,1,6H2,(H,9,10)(H,7,11,12)/t2-/m0/s1
InChi Key
ASNFTDCKZKHJSW-REOHCLBHSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $62

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    5 mg

    $120

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    10 mg

    $207

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    25 mg

    $442

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    Product Description

    L-Quisqualic acid is a natural analog of glutamate that acts as an agonist at AMPA-selective and metabotropic glutamate receptors (EC50s = 170, 10, 40, and 29 nM at GluR-A, mGluR1, mGluR3, and mGluR5, respectively), as well as the ionotropic kainate receptor (GRIK4; Ki = 6.43 nM).1,2,3,4,5,6 L-Quisqualic acid is used to study receptor dynamics and as an excitotoxin to selectively destroy neurons in the brain or spinal cord.7,8

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

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