Pricing updated 2018-10-21. Prices are subject to change without notice.
Vitamin A, also known as all-trans retinol, is an intermediate in retinol metabolism in animals. It is metabolized to retinoic acid (Item No. 11017), a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR). RAR and RXR heterodimerize and act as ligand-dependent transcriptional regulators, with roles in development, reproduction, immunity, organogenesis, and cancer.1,2,3
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Duong, V., and Rochette-
3. Dollé, P. Developmental expression of retinoic acid receptors (RARs). Nucl. Recept. Signal 7, 1-13 (2009).