A ratiometric fluorescent calcium indicator
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Alternative(s)
19531Fura-2 (potassium salt)
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Fura-2 (sodium salt)

Item No. 20414

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2,2'-((2-(2-((6-(bis(carboxylatomethyl)amino)-2-(5-carboxylatooxazol-2-yl)benzofuran-5-yl)oxy)ethoxy)-4-methylphenyl)azanediyl)diacetate, pentasodium salt
Molecular Formula
C29H22N3O14 • 5Na
Formula Weight
751.5
Purity
≥90%
Emission
512 nm (low2+), 505 nm (high [Ca2+])
Excitation
362 nm (low Ca2+), 335 nm (high [Ca2+])
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Water: soluble
SMILES
[O-]C(CN(C1=CC2=C(C=C(C3=NC=C(C([O-])=O)O3)O2)C=C1OCCOC(C=C(C)C=C4)=C4N(CC([O-])=O)CC([O-])=O)CC([O-])=O)=O.[Na+].[Na+].[Na+].[Na+].[Na+]
InChi Code
InChI=1S/C29H27N3O14.5Na/c1-15-2-3-17(31(11-24(33)34)12-25(35)36)20(6-15)43-4-5-44-21-7-16-8-22(28-30-10-23(46-28)29(41)42)45-19(16)9-18(21)32(13-26(37)38)14-27(39)40;;;;;/h2-3,6-10H,4-5,11-14H2,1H3,(H,33,34)(H,35,36)(H,37,38)(H,39,40)(H,41,42);;;;;/
InChi Key
AQVFPZSLWPIFBY-UHFFFAOYSA-I
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $117

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    Product Description

    Fura-2 is a ratiometric fluorescent calcium indicator that can be used to detect calcium in cells.1 It is a pentacarboxylate that displays excitation maxima of 340 and 380 nm at high and low calcium concentrations, respectively, when the emission is fixed at 510 nm, enabling determination of ratiometric measurements of calcium influx in live cells.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kong, S.K., and Lee, C.Y. The use of fura 2 for measurement of free calcium concentration. Biochem. Mol. Biol. Ed. 23(2), 97-98 (1995).