A sym-triazine with diverse biological activities
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

TAE-1

Item No. 20464

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2,2',2'-[1,3,5-triazine-2,4,6-triyltris(oxy-4,1-phenylenecarbonyloxy)]tris[N,N,N-trimethyl-ethanaminium, triiodide
CAS Number
1414469-59-2
Molecular Formula
C39H51N6O9 • 3I
Formula Weight
1128.6
Purity
≥95%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
Acetonitrile: 5 mg/mlDMF: 20 mg/mlDMSO: 20 mg/mlEthanol: Partially solublePBS (pH 7.2): 5 mg/ml
λmax
224 nm
SMILES
O=C(OCC[N+](C)(C)C)C(C=C1)=CC=C1OC2=NC(OC3=CC=C(C(OCC[N+](C)(C)C)=O)C=C3)=NC(OC4=CC=C(C(OCC[N+](C)(C)C)=O)C=C4)=N2.[I-].[I-].[I-]
InChi Code
InChI=1S/C39H51N6O9.3HI/c1-43(2,3)22-25-49-34(46)28-10-16-31(17-11-28)52-37-40-38(53-32-18-12-29(13-19-32)35(47)50-26-23-44(4,5)6)42-39(41-37)54-33-20-14-30(15-21-33)36(48)51-27-24-45(7,8)9;;;/h10-21H,22-27H2,1-9H3;3*1H/q+3;;;/p-3
InChi Key
SGOMELGTKOLYEZ-UHFFFAOYSA-K
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    5 mg

    $28

    Add

    10 mg

    $44

    Add

    25 mg

    $90

    Add
    Product Description

    TAE-1 is a sym-triazine with diverse biological activities.1 It inhibits in vitro amyloid-β (1-42) (Aβ42; Item No. 20574) fibrilization when used at a concentration of 20 µM. TAE-1 inhibits acetylcholinesterase (AChE; IC50 = 0.465 µM for the human erythrocyte enzyme). It also increases neuronal cellular process length and branching and synaptophysin protein levels in differentiated human SH-SY5Y neuronal cells.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Veloso, A.J., Chow, A.M., Dhar, D., et al. Biological activity of sym-triazines with acetylcholine-like substitutions as multitarget modulators of Alzheimer’s disease. ACS Chem. Neurosci. 4(6), 924-929 (2013).