A fluorogenic dye
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Phalloidin-Fluorescein Conjugate

Item No. 20478

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Molecular Formula
C56H59N9O16S
Formula Weight
1146.2
Purity
≥90%
Emission
517 nm
Excitation
498 nm
Formulation (Request formulation change)
A solution in DMSO (1000X)
Solubility(Learn about Variance in Solubility)
DMF: SolubleDMSO: SolubleMethanol: Soluble
SMILES
OC(CC(C(NC(C(NC(C(O)C)C(N1)=O)=O)C)=O)NC(C2NC(C(NC(C(CC(O)C3)N3C(C1CSC4=C(C2)C5=C(C=CC=C5)N4)=O)=O)C)=O)=O)(C)CNC(C6=CC(C(O)=O)=C(C7=C(C=C8)C(OC9=C7C=CC(O)=C9)=CC8=O)C=C6)=O
InChi Code
InChI=1S/C56H59N9O16S/c1-24-46(70)60-38-19-35-31-7-5-6-8-37(31)63-53(35)82-22-40(54(77)65-21-30(69)16-41(65)51(75)59-24)62-52(76)45(26(3)66)64-47(71)25(2)58-50(74)39(61-49(38)73)20-56(4,80)23-57-48(72)27-9-12-32(36(15-27)55(78)79)44-33-13-10-28(67)17
InChi Key
ZOOOSCCCFUSYBG-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    Phalloidin-fluorescein conjugate is a fluorescent dye used to label actin filaments (F-actin). Phalloidin binds to F-actin and prevents depolymerization.1 It also inhibits the ATP hydrolysis action of F-actin.2 Phalloidin-fluorescein can be used to label tissue, cells, and cell-free preparations that have been formaldehyde-fixed and permeabilized. It displays excitation/emission maxima of 498/517 nm, respectively. Phalloidin-fluorescein can be used at nanomolar concentrations in conjunction with additional dyes for multi-labeling purposes.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lengsfeld, A.M., Löw, I., Wieland, T., et al. Interaction of phalloidin with actin. Proc. Natl. Acad. Sci. USA 71(7), 2803-2807 (1974).

    2. Löw, I., Dancker, P., and Wieland, T. Stabilization of F-actin by phalloidin. Reversal of the destabilizing effect of cytochalasin B. FEBS Lett. 54(2), 263-265 (1975).