Leukotriene F4 (CAS 83851-42-7) | Cayman Chemical
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Leukotriene F4

Item № 20520
CAS № 83851-42-7
Purity ≥97%
product image
                (CAS 83851-42-7)
SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     25 µg $108.00 0.00
     50 µg $205.00 0.00
     100 µg $389.00 0.00

Pricing updated 2018-11-19. Prices are subject to change without notice.

Description
Synonyms
  • LTF4

LTF4 is a cysteinyl-leukotriene produced in vitro, but not reported to date in vivo. It is formed by the incubation of LTE4 with γ-glutamyl transpeptidase and glutathione. LTF4 is a weak agonist in its ability to contract vascular smooth muscle.1 The rank order of potency of the cysteinyl-leukotrienes to contract vascular smooth muscle is LTD4 > LTC4 > LTE4 >> LTF4.1,2

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Technical Information
Formal Name
5S-hydroxy-6R-(S-γ-glutamylcysteinyl)-7E,9E,11Z,14Z-eicosatetraenoic acid
CAS Number
83851-42-7
Synonyms
  • LTF4
Molecular Formula
C28H44N2O8S
Formula Weight
568.7
Purity
≥97%
Formulation
A solution in methanol
λmax
280 nm
SMILES
CCCCC/C=C\C/C=C\C=C\C=C\[C@@H](SC[C@H](NC(CC[C@H](N)C(O)=O)=O)C(O)=O)[C@@H](O)CCCC(O)=O
InChI Code
InChI=1S/C28H44N2O8S/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-24(23(31)15-14-17-26(33)34)39-20-22(28(37)38)30-25(32)19-18-21(29)27(35)36/h6-7,9-13,16,21-24,31H,2-5,8,14-15,17-20,29H2,1H3,(H,30,32)(H,33,34)(H,35,36)(H,37,38)/b7-6-,10-9-,12-11+,16-13+/t21-,22
InChI Key
PYSODLWHFWCFLV-BJAXAWPRSA-N

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
Stability
≥ 1 year
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Additional Information

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References & Product Citations
Product Description References

1. Bernstrom, K., and Hammarström, S. A novel leukotriene formed by transpeptidation of leukotriene E4 Biochemical and Biophysical Research Communications 109, 800-804 (1982).

2. Lord, A., Charleson, S., and Letts, L.G. Leukotriene F4 and the release of arachidonic acid metabolites from perfused guinea pig lungs in vitro Prostaglandins 29, 651-660 (1985).

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