A fluorogenic dye
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Phalloidin-iFluor™ 647 Conjugate

Item No. 20555

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Purity
≥90%
Emission
665 nm
Excitation
650 nm
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Phalloidin-iFluor™ 647 Conjugate is a fluorescein-based dye used to label actin filaments (F-actin). Phalloidin binds to F-actin and prevents depolymerization.1 It also inhibits the ATP hydrolysis action of F-actin.2 Phalloidin-iFluor™ 647 can be used to label tissue, cells, and cell-free preparations that have been formaldehyde-fixed and permeabilized. It displays excitation/emission spectra of 650/665 nm, respectively. Phalloidin-iFluor™ 647 can be used at nanomolar concentrations in conjunction with additional dyes for multi-labeling purposes.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lengsfeld, A.M., Löw, I., Wieland, T., et al. Interaction of phalloidin with actin. Proc. Natl. Acad. Sci. USA 71(7), 2803-2807 (1974).

    2. Löw, I., Dancker, P., and Wieland, T. Stabilization of F-actin by phalloidin. Reversal of the destabilizing effect of cytochalasin B. FEBS Lett. 54(2), 263-265 (1975).

    Product Citations

    Moehlman, A.T., Kanfer, G., and youle, R.J. Loss of STING in parkin mutant flies suppresses muscle defects and mitochondria damage. PLos Genet. 19(7), e1010828 (2023).