An broad spectrum antibiotic
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Kijanimicin

Item No. 20586

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-[(O-2,6-dideoxy-α-L-ribo-hexopyranosyl-(1→3)-O-[2,6-dideoxy-4-O-methyl-β-L-ribo-hexopyranosyl-(1→4)]-O-2,6-dideoxy-α-L-ribo-hexopyranosyl-(1→3)-2,6-dideoxy-α-L-ribo-hexopyranosyl)oxy]-2,3S,4S,4aS,6aS,9,10S,12aS,15R,16,20a,20bR-dodecahydro-21-hydroxy-14-(hydroxylmethyl)-1S,3,7E,11E,15,20aS-hexamethyl-10-[[2,3,4,6-tetradeoxy-4-[(methoxycarbonyl)amino]-3-C-methyl-3-nitro-β-D-xylo-hexopyranosyl]oxy]-18H-16aS,19-Metheno-16aH-benzo[b]naphth[2,1-j]oxacyclotetradecin-18,20(1H)-dione
CAS Number
78798-08-0
Synonyms
  • NSC 329515
Molecular Formula
C67H100N2O24
Formula Weight
1317.5
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: solubleDMSO: solubleEthanol: solubleMethanol: soluble
SMILES
O[C@H]([C@H](O)C1)[C@H](C)O[C@@]1([H])O[C@H](C2)[C@@H](O[C@]3([H])C[C@@H](O)[C@@H](OC)[C@H](C)O3)[C@H](C)O[C@@]2([H])O[C@H](C4)[C@@H](O)[C@H](C)O[C@@]4([H])O[C@@H]5[C@]6([H])[C@@]([C@@](C(C7=C8O)=O)(C)[C@@](/C(C)=C\C[C@H](O[C@]9([H])O[C@H](C)[C@H](NC
InChi Code
InChI=1S/C67H100N2O24/c1-29-15-18-45(88-52-27-65(11,69(79)80)60(38(10)87-52)68-64(78)82-14)30(2)20-40-21-39(28-70)33(5)26-67(40)62(76)53(63(77)93-67)61(75)66(12)42(29)17-16-41-54(66)31(3)19-32(4)57(41)91-51-24-46(56(74)35(7)84-51)89-50-25-47(90-48-22
InChi Key
AAHYWTFSLXCSNH-DFHQFNTBSA-N
Origin
Bacterium/Actinomadura sp.
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

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    500 µg

    $380

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    2.5 mg

    $1,234

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    Cayman Chemical
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    Product Description

    Kijanimicin is an antibiotic first isolated from the fermentation broth of A. kijaniata SCC 1256.1 It is active against a broad spectrum of microorganisms in vitro including P. acnes (MIC = 0.86 µg/ml), B. subtilis (MIC < 0.13 µg/ml), Enterobacter sp. (MIC = 64 µg/ml), Trichophyton sp. (MIC = 17.5 µg/ml), and Microsporum sp. (MIC = 17.5 µg/ml).1 At 250 mg/kg, kijanimicin was also shown to be effective in mice against P. berghei, a protozoan parasite that causes malaria in certain rodents.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Waitz, J.A., Horan, A.C., Kalyanpur, M., et al. Kijanimicin (Sch 25663), a novel antibiotic produced by Actinomadura kijaniata SCC 1256. Fermentation, isolation, characterization and biological properties. J. Antibiot. (Tokyo) 34(9), 1101-1106 (1981).