An antibiotic used in clotting assays
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Product Categories

Product Type

Biochemicals

Research Area

Cardiovascular System
Blood
Acute Phase Reactants

Ristocetin A (sulfate)

Item No. 20601

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
ristomycin A, monosulfate
CAS Number
90831-71-3
Synonyms
  • Ristomycin III
Molecular Formula
C95H112N8O44 • XSO4
Formula Weight
2070.0
Purity
≥85%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: SolubleDMSO: SolubleEthanol: SolubleMethanol: Soluble
SMILES
OC(C=CC1=C2)=C2C3=C([C@@H](C(OC)=O)NC([C@](NC([C@]1([H])NC4=O)=O)([H])[C@H](O[C@@]5([H])C[C@@H]([NH3+])[C@@H](O)[C@H](C)O5)C6=CC=C(OC7=CC([C@@]4([H])NC([C@@](C8=CC(O)=C(C)C(OC9=C(O)C=CC%10=C9)=C8)([H])NC([C@]([C@H](O)C(C=C%11)=CC=C%11O%12)([H])NC([C@
InChi Code
InChI=1S/C95H110N8O44.H2O4S/c1-30-47(109)18-37-20-49(30)139-50-19-35(9-16-46(50)108)59(97)84(125)102-64-68(113)33-5-11-40(12-6-33)137-52-21-38-22-53(81(52)145-95-83(76(121)72(117)56(143-95)29-134-91-78(123)73(118)67(112)32(3)136-91)147-94-82(75(120)7
InChi Key
HHRPQUHYQBGHHF-HGRVMTQKSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    10 mg

    $308

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    50 mg

    $923

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    Product Description

    Ristocetin A is an antibiotic that was used to treat staphylococcal infections.1 However, side effects of ristocetin A included thrombocytopenia and platelet agglutination. Ristocetin A is now used in two assays related to these actions, the ristocetin cofactor assay and the ristocetin-induced platelet aggregation assay. Both assays are used in the diagnosis of von Willebrand disease and other bleeding disorders.2,1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hawks, G.H. Antibiotic therapy of staphylococcal infection. Can. Med. Assoc. J. 93(16), 848-853 (1965).

    2. Castaman, G., Hillarp, A., and Goodeve, A. Laboratory aspects of von Willebrand disease: Test repertoire and options for activity assays and genetic analysis. Haemophilia 20(suppl 4), 65-70 (2014).