An antiarrhythmic agent
Related Products
Isomer(s)
20388Flecainide (acetate)
Technical Support & Resources

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Product Categories

Product Type

Biochemicals

Research Area

Cardiovascular System
Heart
Arrhythmia

R-(–)-Flecainide

Item No. 20682

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-[(2R)-2-piperidinylmethyl]-2,5-bis(2,2,2-trifluoroethoxy)-benzamide
CAS Number
99495-90-6
Molecular Formula
C17H20F6N2O3
Formula Weight
414.3
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Ethanol: solubleMethanol: soluble
SMILES
O=C(NC[C@H]1CCCCN1)C2=C(OCC(F)(F)F)C=CC(OCC(F)(F)F)=C2
InChi Code
InChI=1S/C17H20F6N2O3/c18-16(19,20)9-27-12-4-5-14(28-10-17(21,22)23)13(7-12)15(26)25-8-11-3-1-2-6-24-11/h4-5,7,11,24H,1-3,6,8-10H2,(H,25,26)/t11-/m1/s1
InChi Key
DJBNUMBKLMJRSA-LLVKDONJSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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Download most recent Certificate of Analysis for this product

    500 µg

    $113

    Add

    1 mg

    $225

    Add
    Product Description

    R-(–)-Flecainide is the (R) enantiomer of the antiarrhythmic agent flecainide (Item No. 20388).1 R-(–)-Flecainide prevents chloroform-induced ventricular fibrillation in mice (ED50 = 14.5 mg/kg). It also prevents ouabain-induced ectopic ventricular tachycardia in anesthetized dogs.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Banitt, E.H., Schmid, J.R., and Newmark, R.A. Resolution of flecainide acetate, N-(2-piperidylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide acetate, and antiarrhythmic properties of the enantiomers. J. Med. Chem. 29(2), 299-302 (1986).