A cell-permeant, vital fluorescent dye
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Product Categories

Product Type

Biochemicals
Labeling & Detection
Fluorescent Probes

Research Area

Application

Flow Cytometry
Fluorescence

CytoTrace™ Orange CMTMR

Item No. 20696

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
9-[2-carboxy-4(or 5)-[[4-(chloromethyl)benzoyl]amino]phenyl]-3,6-bis(dimethylamino)-xanthylium, inner salt
CAS Number
323192-14-9
Synonyms
  • CellTracker™ Orange CMTMR
Molecular Formula
C32H28ClN3O4
Formula Weight
554.0
Purity
≥90%
Emission
565 nm
Excitation
541 nm
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble
SMILES
CN(C)C(C=C1)=CC2=C1C(C3=CC=C(NC(C4=CC=C(CCl)C=C4)=O)C=C3C([O-])=O)=C(C=CC(N(C)C)=C5)C5=[O+]2.CN(C)C(C=C6)=CC7=C6C(C8=CC(NC(C9=CC=C(CCl)C=C9)=O)=CC=C8C([O-])=O)=C(C=CC(N(C)C)=C%10)C%10=[O+]7
InChi Code
InChI=1S/2C32H28ClN3O4/c1-35(2)22-10-13-25-28(16-22)40-29-17-23(36(3)4)11-14-26(29)30(25)27-15-21(9-12-24(27)32(38)39)34-31(37)20-7-5-19(18-33)6-8-20;1-35(2)22-10-13-25-28(16-22)40-29-17-23(36(3)4)11-14-26(29)30(25)24-12-9-21(15-27(24)32(38)39)34-31(
InChi Key
OGCVKCZFRAJETN-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    50 µg

    $69

    Add
    Product Description

    CytoTrace™ Orange CMTMR is a rhodamine-based, cell-permeant, vital fluorescent dye that is retained by cells for prolonged periods (>72 hours) and is passed to daughter cells. Cells loaded with long-lasting dyes, including CMTMR, are used to follow cell trafficking and cell-to-cell interactions in vivo.1,2,3 They have also been used to estimate the growth of implanted tumor spheroids.4 CytoTrace™ Orange CMTMR displays excitation/emission maxima of 541/565 nm, respectively.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Brooks, A.E.S., Parsamand, T., Kelly, R.W., et al. An improved quantitative method to assess adhesive properties of Trichomonas vaginalis to host vaginal ectocervical cells using flow cytometry. J. Microbiol. Methods 92(1), 73-78 (2013).

    2. Buehler, C., Dong, C.Y., So, P.T.C., et al. Time-resolved polarization imaging by pump-probe (stimulated emission) fluorescence microscopy. Biophys J. 79(1), 536-549 (2000).

    3. Sato, K., Imai, Y., and Irimura, T. Contribution of dermal macrophage trafficking in the sensitization phase of contact hypersensitivity. J. Immunol. 161(12), 6835-6844 (1998).

    4. Borgström, P., Hillan, K.J., Sriramarao, P., et al. Complete inhibition of angiogenesis and growth of microtumors by anti-vascular endothelial growth factor neutralizing antibody: Novel concepts of angiostatic therapy from intravital videomicroscopy. Cancer Res. 56(17), 4032-4039 (1996).