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Explore how neutrophils shape the immune response in health and disease. This poster highlights neutrophil pathogen defense mechanisms, including phagocytosis, degranulation, and NETosis, as well as neutrophil roles in inflammation and NET-associated pathologies.
DOWNLOAD NOWAN2718 is a benzoxaborole compound that displays broad antifungal effectiveness in vitro.1 It inhibits leucyl-tRNA synthetase (LeuRS) from molds and yeasts (IC50s = 2 and 4.2 µM for A. fumigatus and C. albicans LeuRS, respectively), blocking protein synthesis.1
WARNING This product is not for human or veterinary use.
1. Antifungal activity and mechanism of action of a benzoxaborole, AN2718, which is in development for the treatment of tinea pedis. 48th Annual ICAAC/46th Annual IDSA (2008).