For the immunochemical detection of H3K4me3
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Histone H3K4Me3 Rabbit Monoclonal Antibody (Clone RM137)

Item No. 20718

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Immunogen
A trimethyl-peptide corresponding to trimethyl-histone H3 (Lys4)
Clone Designation
RM137
Formulation (Request formulation change)
100 μg of protein A-affinity purified antibody from an animal origin free culture supernatant
Storage Buffer
PBS with 50% glycerol, 1% BSA, and 0.09% sodium azide
Host
Rabbit
Isotype
IgG
Applications
ELISA, multiplex-based assays, WB
Cross Reactivity
(+) Histone H3 trimethylated at lysine 4 (K4me3)(-) Monomethylated lysine 4 (K4me1)(-) Dimethylated lysine 4 (K4me2)(-) Other methylations in histone H3
Species Reactivity
(+) All species
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

    100 µg

    $500

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    Product Description

    Histone H3 undergoes many modifications including acetylation, methylation, and phosphorylation that are important for regulation of gene transcription. Methylation at lysine 4 of histone 3 (H3K4) is an evolutionarily conserved modification associated with transcriptionally active chromatin. The SET1/MLL (KMT2) family of methyltransferases is the principal enzyme family responsible for H3K4 methylations. This antibody reacts to histone H3 trimethylated at lysine 4 (K4me3) and does not detect monomethylated lysine 4 (K4me1), dimethylated lysine 4 (K4me2), or other methylations in histone H3.

    WARNING This product is not for human or veterinary use.