A natural ω-6 PUFA
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13Z,16Z-Docosadienoic Acid

Item No. 20749

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
13Z,16Z-docosadienoic acid
CAS Number
17735-98-7
Synonyms
  • cis-13,16-Docosadienoic Acid
  • FA 22:2
Molecular Formula
C22H40O2
Formula Weight
336.6
Purity
≥98%
Formulation (Request formulation change)
A 10 mg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMSO: 10 mg/mlEthanol: 10 mg/mlPBS (pH 7.2): 0.5 mg/ml
SMILES
CCCCC/C=C\C/C=C\CCCCCCCCCCCC(O)=O
InChi Code
InChI=1S/C22H40O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24/h6-7,9-10H,2-5,8,11-21H2,1H3,(H,23,24)/b7-6-,10-9-
InChi Key
HVGRZDASOHMCSK-HZJYTTRNSA-N
Side Chain Carbon Sum
22:2
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1 mg

    $37

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    5 mg

    $132

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    10 mg

    $176

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    Product Description

    13Z,16Z-Docosadienoic acid is a natural ω-6 polyunsaturated fatty acid (PUFA). It is an agonist of free fatty acid receptor 4 (FFAR4, also known as GPR120) and strongly inhibits the secretion of ghrelin by isolated mouse gastric cells.1 This 20:2 PUFA has been identified in mammals, fish, plants, and anaerobic fungi.2,3,4,5,6

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lu, X., Zhao, X., Feng, J., et al. Postprandial inhibition of gastric ghrelin secretion by long-chain fatty acid through GPR120 in isolated gastric ghrelin cells and mice. Am. J. Physiol. Gastrointest. Liver Physiol. 303(3), G367-376 (2012).

    2. de Oliveira, A.P., de Souza Franco, E., Barreto, R.R., et al. Effect of semisolid formulation of persea americana mill (avocado) oil on wound healing in rats. Evid. Based Complement. Altnernat. Med. 472382 (2013).

    3. Gonzales, G.F., Gonzales, C., and Villegas, L. Exposure of fatty acids after a single oral administration of sacha inchi (Plukenetia volubilis L.) and sunflower oil in human adult subjects. Toxicol. Mech. Methods 24(1), 60-69 (2014).

    4. Kim, S.-W., John, M., Kin, J.M., et al. Relationship between erythrocyte fatty acid composition and psychopathology in the vienna Omega-3 study. PLoS One 11(3), e0151417 (2016).

    5. Koppová, I., Novotná, Z., Štrosová, L., et al. Analysis of fatty acid composition of anaerobic rumen fungi. Folia Microbiol. (Praha) 53(3), 217-220 (2008).

    6. Wågbø, A.M., Canigalosi, M.V., Ciero, N., et al. Perfluorooctane sulfonamide-mediated modulation of hepatocellular lipid homeostasis and oxidative stress responses in Atlantic salmon hepatocytes. Chem. Res. Toxicol. 25(6), 1253-1264 (2012).