A reagent used in fluorescence, spectroscopy, and microbiology techniques
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Product Type

Biochemicals
Labeling & Detection

Research Area

Application

Fluorescence

1-Thioglycerol

Item No. 20824

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3-mercapto-1,2-propanediol
CAS Number
96-27-5
Synonyms
  • 3-Mercaptopropane-1,2-diol
  • (±)-3-Mercapto-1,2-propanediol
  • NSC 5370
  • 2,3-dihydroxy Propanethiol
  • 1-Thio-2,3-propanediol
Molecular Formula
C3H8O2S
Formula Weight
108.2
Purity
≥98%
Formulation (Request formulation change)
A neat oil
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMSO: 10 mg/mlEthanol: 30 mg/mlEthanol:PBS (pH 7.2)(1:2): 0.25 mg/ml
SMILES
SCC(O)CO
InChi Code
InChI=1S/C3H8O2S/c4-1-3(5)2-6/h3-6H,1-2H2
InChi Key
PJUIMOJAAPLTRJ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $25

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    5 mg

    $75

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    10 mg

    $117

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    25 mg

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    Product Description

    1-Thioglycerol is a reagent used in fluorescence, spectroscopy, and microbiology techniques. Varying the concentration of 1-thioglycerol in the preparation of CdSe/CdS core-shell ultrasmall quantum dots (CS-USQDs) allows a precise way to control the size of the shell, with shell size increasing with increased concentration.1 It is used as a capping agent in the synthesis of nanocrystals analyzed via Raman and UV/Vis spectroscopy.2,3 Biologically, 1-thioglycerol stimulates porphyrin synthesis and increases glutamyl-tRNA reductase activity in E. coli grown in an aerobic environment.4 It was previously a component in hair permanents used to produce waves or curls.5

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Silva, A.C.A., da Silva, S.W., Morais, P.C., et al. Shell thickness modulation in ultrasmall CdSe/CdSxSe1-x/CdS core/shell quantum dots via 1-thioglycerol. ACS Nano 8(2), 1913-1922 (2014).

    2. Wang, Y., Sun, Z., Hu, H., et al. Raman scattering study of molecules adsorbed on ZnS nanocrystals. J. Raman Spect. 38(1), 34-38 (2007).

    3. Harrison, M.T., Kershaw, S.V., Rogach, A.L., et al. Wet chemical synthesis of highly luminescent HgTe/CdS core/shell nanocrystals. Adv. Mat. 12(2), 123-125 (2000).

    4. Javor, G.T., and Febre, E.F. Enzymatic basis of thiol-stimulated secretion of porphyrins by Escherichia coli. J. Bacteriol. 174(3), 1072-1075 (1992).

    5. Lehman, A.J. Health aspects of common chemicals used in hair-waving preparations. JAMA 141(12), 842-845 (1949).