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Ganaxolone

Item No. 20919

Restricted Product (Schedule V)
Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • CCD 1042
Technical Information
Formal Name
(3α,5α)-3-hydroxy-3-methyl-pregnan-20-one
CAS Number
38398-32-2
Molecular Formula
C22H36O2
Formula Weight
332.5
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
Acetonitrile: 1 mg/mlEthanol: 1 mg/mlMethanol: 1 mg/ml
λmax
282 nm
SMILES
C[C@@]12[C@](CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@@H]4C(C)=O)([H])C[C@](C)(O)CC1
InChi Code
InChI=1S/C22H36O2/c1-14(23)17-7-8-18-16-6-5-15-13-20(2,24)11-12-21(15,3)19(16)9-10-22(17,18)4/h15-19,24H,5-13H2,1-4H3/t15-,16-,17+,18-,19-,20+,21-,22+/m0/s1
InChi Key
PGTVWKLGGCQMBR-FLBATMFCSA-N
Regulatory Information
DEA Schedule
V
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    Product Description

    Ganaxolone (Item No. 20919) is an analytical reference standard categorized as a GABAA receptor positive allosteric modulator.1 Ganaxolone has anticonvulsant activity in mice. Ganaxolone is regulated as a Schedule V compound in the United States. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Carter, R.B., Wood, P.L., Wieland, S., et al. Characterization of the anticonvulsant properties of ganaxolone (CCD 1042; 3α-hydroxy-3β-methyl-5α-pregnan-20-one), a selective, high-affinity, steroid modulator of the γ-aminobutyric acidA receptor. J. Pharmacol. Exp. Ther. 280(3), 1284-1295 (1997).