A phospholipid
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1-Palmitoyl-2-Linoleoyl-sn-glycero-3-PC

Item No. 20962

Technical Information
Formal Name
(7R,17Z,20Z)-4-hydroxy-N,N,N-trimethyl-9-oxo-7-[[(1-oxohexadecyl)oxy]methyl]-3,5,8-trioxa-4-phosphahexacosa-17,20-dien-1-aminium-4-oxide, inner salt
CAS Number
17708-90-6
Synonyms
  • 1-Palmitoyl-2-Linoleoyl-sn-glycero-3-Phosphatidylcholine
  • 16:0-18:2 PC
  • PLPC
Molecular Formula
C42H80NO8P
Formula Weight
Purity
≥95% (9:1 mixture of 1':2' acyl chain positional isomers)
A 10 mg/ml solution in ethanol
Chloroform: Soluble: ≥ 10 mg/mlEthanol: 50 mg/mlEthanol: Soluble: ≥ 10 mg/mlEthanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
SMILES
O=C(CCCCCCCCCCCCCCC)OC[C@@H](OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COP([O-])(OCC[N+](C)(C)C)=O
InChi Code
InChI=1S/C42H80NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h14,16,20-21,40H,6-13,15,17-19,22-39H2,1-5H3/b16-14-,21-20-/t40-/m1/s1
InChi Key
JLPULHDHAOZNQI-ZTIMHPMXSA-N
Side Chain Carbon Sum
34:2
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    1-Palmitoyl-2-Linoleoyl-sn-glycero-3-PC is a phospholipid containing palmitic (16:0) and linoleic (18:2) acids inserted at the sn-1 and sn-2 positions, respectively. It can be used in the generation of micelles, liposomes, and other types of artificial membranes and has been particularly useful in the study of lipid peroxidation.1,2,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Conte, E., Megli, F.M., Khandelia, H., et alLipid peroxidation and water penetration in lipid bilayers: A W-band EPR study. Biochim. Biophys. Acta 1828, 510-517 (2013).

    2. Milne, G.L., Seal, J.R., Havrilla, C.M., et alIdentification and analysis of products formed from phospholipids in the free radical oxidation of human low density lipoproteins. J. Lipid Res. 46(2), 307-319 (2005).

    3. Høyrup, P., Mouritsen, O.G., and Jørgensen, K. Phospholipase A2 activity towards vesicles of DPPC and DMPC-DSPC containing small amounts of SMPC. Biochim. Biophys. Acta 1515(2), 133-143 (2001).