An indole alkaloid
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Tryptamine

Item No. 20995

Technical Information
Formal Name
1H-indole-3-ethanamine
CAS Number
61-54-1
Synonyms
  • 3-Indoleethylamine
  • NSC 165212
Molecular Formula
C10H12N2
Formula Weight
Purity
≥98%
A crystalline solid
DMF: 5 mg/mlDMSO: 11 mg/mlDMSO:PBS (pH 7.2) (1:1): 0.5 mg/mlEthanol: 10 mg/ml
λmax
220, 282, 290 nm
SMILES
NCCC1=CNC2=CC=CC=C21
InChi Code
InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2
InChi Key
APJYDQYYACXCRM-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Tryptamine is an indole alkaloid and intermediate in the biosynthesis of serotonin and the phytohormone melatonin in plants.1,2 It increases the levels of the terpenoid indole alkaloids ajmalicine, strictosidine, and catharanthine in cultures of C. roseus.3 Tryptamine is also a product of tryptophan metabolism in mammals.4 Tryptamine derivatives have been synthetically produced as hallucinogenic drugs of abuse that act on the serotonergic system.5

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Arnao, M.B. Phytomelatonin: Discovery, content, and role in plants. Adv. Bot. 2014:815769, (2014).

    2. Fan, J., Xie, Y., Zhang, Z., et alMelatonin: A multifunctional factor in plants. Int. J. Mol. Sci. 19(5), E1528 (2018).

    3. Almagro, L., Fernández-Pérez, F., and Pedreño, M.A. Indole alkaloids from Catharanthus roseus: Bioproduction and their effect on human health. Molecules 20(2), 2973-3000 (2015).

    4. Berumen, L.C., Rodríguez, A., Miledi, R., et alSerotonin receptors in hippocampus. Sci. World J. 2012:823493, (2012).

    5. Araujo, A.M., Carvalho, F., Bastos, M.L., et alThe hallucinogenic world of tryptamines: An updated review. Arch. Toxicol. 89(8), 1151-1173 (2015).