A semisynthetic penicillin antibiotic
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Methicillin (sodium salt)

Item No. 21007

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(2S,5R,6R)-6-[(2,6-dimethoxybenzoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, monosodium salt
CAS Number
132-92-3
Synonyms
  • BRL 1241
  • SQ 16,123
  • X 1497
Molecular Formula
C17H19N2O6S • Na
Formula Weight
402.4
Purity
≥90%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMSO: 16 mg/mlEthanol: 2 mg/mlPBS (pH 7.2): 10 mg/ml
λmax
280, 330 nm
SMILES
O=C(N[C@@H]1C(N2[C@]1([H])SC(C)(C)[C@@H]2C([O-])=O)=O)C3=C(OC)C=CC=C3OC.[Na+]
InChi Code
InChI=1S/C17H20N2O6S.Na/c1-17(2)12(16(22)23)19-14(21)11(15(19)26-17)18-13(20)10-8(24-3)6-5-7-9(10)25-4;/h5-7,11-12,15H,1-4H3,(H,18,20)(H,22,23);/q;+1/p-1/t11-,12+,15-;/m1./s1
InChi Key
MGFZNWDWOKASQZ-UMLIZJHQSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Methicillin is a semisynthetic penicillin antibiotic that can inhibit bacterial cell wall synthesis.1 It can be used to study methicillin-resistance in S. aureus.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hawks, G.H. Antibiotic therapy of staphylococcal infection. Can. Med. Assoc. J. 93(16), 848-853 (1965).

    2. Kehrenberg, C., Cuny, C., Strommenger, B., et al. Methicillin-resistant and -susceptible Staphylococcus aureus strains of clonal lineages ST398 and ST9 from swine carry the multidrug resistance gene cfr. Antimicrob. Agents Chemother. 53(2), 779-781 (2009).