A fluorogenic dye
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9-(2,2-Dicyanovinyl)julolidine

Item No. 21016

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-[(2,3,6,7-tetrahydro-1H,5H-benzo[ij]quinolizin-9-yl)methylene]-propanedinitrile
CAS Number
58293-56-4
Synonyms
  • DCVJ
  • 9-Julolidine Methylene Malononitrile
  • NSC 160064
Molecular Formula
C16H15N3
Formula Weight
249.3
Purity
≥98%
Emission
480 nm (low viscosity solvents), 505 nm (high viscosity solvents)
Excitation
450 nm
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMSO: 20 mg/mlDMSO:PBS (pH 7.2) (1:2): 0.33 mg/mlEthanol: 0.2 mg/ml
λmax
455 nm
SMILES
N#C/C(C#N)=C\C1=CC2=C3N(CCC2)CCCC3=C1
InChi Code
InChI=1S/C16H15N3/c17-10-13(11-18)7-12-8-14-3-1-5-19-6-2-4-15(9-12)16(14)19/h7-9H,1-6H2
InChi Key
LROAUBRDKLVBCP-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    5 mg

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    Product Description

    9-(2,2-Dicyanovinyl)julolidine (DCVJ) is a fluorogenic dye that is considered a fluorescent molecular rotor because its properties depend on the rotational relaxation of the molecule, which can be influenced by the viscosity of the solvent used.1 It has an excitation maximum at approximately 450 nm, and its emission is approximately 480 or 505 nm for low or high viscosity solvents, respectively. DCVJ has been used to study tubulin dynamics because its fluorescence increases when bound to tubulin sheets but is lower when bound to microtubules.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kung, C.E., and Reed, J.K. Fluorescent molecular rotors: a new class of probes for tubulin structure and assembly. Biochemistry 28(6), 6678-6686 (1989).