A cofactor in the formation of blood-clotting proteins
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Labeled Version(s)
29992Vitamin K1-d7
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Vitamin K1

Item No. 21051

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-methyl-3-[(2E,7R,11R)-3,7,11,15-tetramethyl-2-hexadecen-1-yl]-1,4-naphthalenedione
CAS Number
84-80-0
Synonyms
  • NSC 270681
  • ɑ-Phylloquinone
  • trans-Phylloquinone
Molecular Formula
C31H46O2
Formula Weight
450.7
Purity
≥80% (allowing less than 20% z isomer)
Formulation (Request formulation change)
A neat oil
Solubility(Learn about Variance in Solubility)
DMF: 25 mg/mlDMSO: 25 mg/mlEthanol: 25 mg/ml
λmax
247, 261, 269, 329 nm
SMILES
O=C1C(C/C=C(C)/CCC[C@H](C)CCC[C@H](C)CCCC(C)C)=C(C)C(C2=CC=CC=C21)=O
InChi Code
InChI=1S/C31H46O2/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-17-25(5)20-21-27-26(6)30(32)28-18-7-8-19-29(28)31(27)33/h7-8,18-20,22-24H,9-17,21H2,1-6H3/b25-20+/t23-,24-/m1/s1
InChi Key
MBWXNTAXLNYFJB-NKFFZRIASA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 g

    $41

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    5 g

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    10 g

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    25 g

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    Cayman Chemical
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    Product Description

    Vitamin K1 is a fat-soluble, dietary nutrient that is essential for the synthesis of proteins important for blood-clotting, bone metabolism, and cell growth.1 It is found in the photosynthetic tissues of green, leafy plants, where it acts as an electron acceptor forming part of the electron transport chain of Photosystem I.2 Vitamin K1 also serves as a precursor to vitamin K2 and is reported to exhibit anticancer activity in various cell lines.3,4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Plaza, S.M., and Lamson, D.W. Vitamin K2 in bone metabolism and osteoporosis. Altern. Med. Rev. 10(1), 24-35 (2005).

    2. Santabarbara, S., Heathcote, P., and Evans, M.C.W. Modelling of the electron transfer reactions in Photosystem I by electron tunnelling theory: The phylloquinones bound to the PsaA and the PsaB reaction centre subunits of PS I are almost isoenergetic to the iron-sulfur cluster FX. Biochim. Biophys. Acta 1708(3), 283-310 (2005).

    3. Beulens, J.W.J., Booth, S.L., van den Heuvel, E.G.H.M., et al. The role of menaquinones (vitamin K2) in human health. Br. J. Nutr. 110(8), 1357-1368 (2013).

    4. Lamson, D.W., and Plaza, S.M. The anticancer effects of vitamin K. Altern. Med. Rev. 8(3), 303-318 (2003).