A cyclic polypeptide antibiotic
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Bacitracin (zinc)

Item No. 21212

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
CAS Number
1405-89-6
Synonyms
  • Bacifarmin
Molecular Formula
C66H101N17O16S • Zn
Formula Weight
1486.1
Purity
≥70% (Bacitracin A,B1,B3 mixture)
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMSO: Slightly Soluble
SMILES
CC[C@@H]([C@H]1C(N[C@H](CC2=CC=CC=C2)C(N[C@@H](CC3=CN=CN3)C(N[C@H](CC([O-])=O)C(N[C@@H](CC(N)=O)C(NCCCC[C@H](NC([C@@H](NC([C@H](NC([C@@H](NC(C4=NC(C(C(CC)C)N)SC4)=O)CC(C)C)=O)CCC([O-])=O)=O)[C@H](CC)C)=O)C(N[C@H](CCCN)C(N1)=O)=O)=O)=O)=O)=O)=O)C.[Zn+2]
InChi Code
InChI=1S/C66H103N17O16S.Zn/c1-9-35(6)52(69)66-81-48(32-100-66)63(97)76-43(26-34(4)5)59(93)74-42(22-23-50(85)86)58(92)83-53(36(7)10-2)64(98)75-40-20-15-16-25-71-55(89)46(29-49(68)84)78-62(96)47(30-51(87)88)79-61(95)45(28-39-31-70-33-72-39)77-60(94)44(27-38-18-13-12-14-19-38)80-65(99)54(37(8)11-3)82-57(91)41(21-17-24-67)73-56(40)90;/h12-14,18-19,31,33-37,40-47,52-54,66H,9-11,15-17,20-30,32,67,69H2,1-8H3,(H2,68,84)(H,70,72)(H,71,89)(H,73,90)(H,74,93)(H,75,98)(H,76,97)(H,77,94)(H,78,96)(H,79,95)(H,80,99)(H,82,91)(H,83,92)(H,85,86)(H,87,88);/q;+2/p-2/t35?,36-,37-,40-,41+,42+,43-,44+,45-,46-,47+,52?,53-,54-,66?;/m0./s1
InChi Key
YDUPIJIVLKNJJG-DAQOJNSOSA-L
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 g

    $29

    Add

    5 g

    $123

    Add

    10 g

    $215

    Add

    25 g

    $469

    Add
    Cayman Chemical
    Neutrophil Biology Wall Poster

    Explore how neutrophils shape the immune response in health and disease. This poster highlights neutrophil pathogen defense mechanisms, including phagocytosis, degranulation, and NETosis, as well as neutrophil roles in inflammation and NET-associated pathologies.

    DOWNLOAD NOW
    Product Description

    Bacitracin is a cyclic polypeptide antibiotic that was first isolated from B. licheniformis.1 Formulations containing bacitracin, often combined with other antibiotics, are used for topical treatment of infections in humans and animals.2,3 The activity of bacitracin can be enhanced by zinc.4 Bacitracin sequesters C55-isopropyl pyrophosphate (IPP), a lipid carrier in peptidoglycan synthesis, and in this way disrupts cell wall biosynthesis.2,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Katz, E., and Demain, A.L. The peptide antibiotics of Bacillus: Chemistry, biogenesis, and possible functions. Bacteriol. Rev. 41(2), 449-474 (1977).

    2. Butaye, P., Devriese, L.A., and Haesebrouck, F. Antimicrobial growth promoters used in animal feed: Effects of less well known antibiotics on gram-positive bacteria. Clin. Microbiol. Rev. 16(2), 175-188 (2003).

    3. Chancey, S.T., Zähner, H., and Stephens, D.S. Acquired inducible antimicrobial resistance in Gram-positive bacteria. Future Microbiol. 7(8), 959-978 (2012).

    4. Astiazarán-García, H., Iñigo-Figueroa, G., Quihui-Cota, L., et al. Crosstalk between zinc status and Giardia infection: A new approach. Nutrients 7(6), 4438-4452 (2015).