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Bendroflumethiazide

Item No. 21311

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • Bendrofluazide
Technical Information
Formal Name
3,4-dihydro-3-(phenylmethyl)-6-(trifluoromethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide-1,1-dioxide
CAS Number
73-48-3
Molecular Formula
C15H14F3N3O4S2
Formula Weight
421.4
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMF:PBS(pH 7.2)(1:1): 0.5 mg/mlDMSO: 10 mg/mlEthanol: 2 mg/ml
λmax
271, 324 nm
SMILES
O=S1(C2=C(C=C(C(F)(F)F)C(S(N)(=O)=O)=C2)NC(CC3=CC=CC=C3)N1)=O
InChi Code
InChI=1S/C15H14F3N3O4S2/c16-15(17,18)10-7-11-13(8-12(10)26(19,22)23)27(24,25)21-14(20-11)6-9-4-2-1-3-5-9/h1-5,7-8,14,20-21H,6H2,(H2,19,22,23)
InChi Key
HDWIHXWEUNVBIY-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Bendroflumethiazide (Item No. 21311) is an analytical reference standard categorized as a diuretic.1,2 Diuretics, including bendroflumethiazide, have been abused as performance-enhancing drugs and masking agents in sports doping.3 This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Majid, D.S.A., and Navar, L.G. Blockade of distal nephron sodium transport attenuates pressure natriuresis in dogs. Hypertension 23(6 Pt 2), 1040-1045 (1994).

    2. Vongpatanasin, W. Hydrochlorothiazide (HCTZ) is not the most useful nor versatile thiazide diuretic. Curr. Opin. Cardiol. 30(4), 361-365 (2015).

    3. Cadwallader, A.B., de la Torre, X., Tieri, A., et al. The abuse of diuretics as performance-enhancing drugs and masking agents in sport doping: Pharmacology, toxicology and analysis. Br. J. Pharmacol. 161(1), 1-16 (2010).