A chloramphenicol-derived antibiotic
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Thiamphenicol

Item No. 21357

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl]-acetamide
CAS Number
15318-45-3
Synonyms
  • NSC 522822
  • (+)-Thiamphenicol
  • Thiophenicol
  • WIN 5,603-2
Molecular Formula
C12H15Cl2NO5S
Formula Weight
356.2
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlDMSO:PBS (pH 7.2) (1:1): 0.5 mg/mlEthanol: 200 µg/ml
λmax
225, 266 nm
SMILES
CS(C1=CC=C([C@@H](O)[C@H](NC(C(Cl)Cl)=O)CO)C=C1)(=O)=O
InChi Code
InChI=1S/C12H15Cl2NO5S/c1-21(19,20)8-4-2-7(3-5-8)10(17)9(6-16)15-12(18)11(13)14/h2-5,9-11,16-17H,6H2,1H3,(H,15,18)/t9-,10-/m1/s1
InChi Key
OTVAEFIXJLOWRX-NXEZZACHSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    5 g

    $63

    Add

    10 g

    $110

    Add

    25 g

    $229

    Add

    50 g

    $423

    Add
    Cayman Chemical
    Neutrophil Biology Wall Poster

    Explore how neutrophils shape the immune response in health and disease. This poster highlights neutrophil pathogen defense mechanisms, including phagocytosis, degranulation, and NETosis, as well as neutrophil roles in inflammation and NET-associated pathologies.

    DOWNLOAD NOW
    Product Description

    Thiamphenicol is an antibiotic derived from chloramphenicol that displays a similar spectrum of activity with enhanced potency.1,2,3 It displays good in vitro activity against a range of multidrug resistant pathogens, including penicillin-resistant strains and methicillin-resistant S. aureus.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Feder, H.M., Jr., Osier, C., and Maderazo, E.G. Chloramphenicol: A review of its use in clinical practice. Rev. Infect. Dis. 3(3), (1981).

    2. Marchese, A., Debbia, E.A., Tonoli, E., et al. In vitro activity of thiamphenicol against multiresistant Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus in Italy. J. Chemother. 14(6), 554-561 (2002).

    3. Raymond, J., Boutros, N., and Bergeret, M. Role of thiamphenicol in the treatment of community-acquired lung infections. Med. Trop. (Mars) 64(1), 33-38 (2004).