A biotinylation reagent
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Biotin LC hydrazide

Item No. 21497

Technical Information
Formal Name
6-[[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]-hexanoic acid hydrazide
CAS Number
109276-34-8
Synonyms
  • 6-BACH
  • Biotinamidocaproyl hydrazide
  • (+)-Biotinamidohexanoic Acid hydrazide
Molecular Formula
C16H29N5O3S
Formula Weight
Purity
≥98%
A crystalline solid
DMSO: 5 mg/mlDMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
SMILES
O=C1N([H])[C@]2([H])[C@]([C@H](CCCCC(N(CCCCCC(N(N)[H])=O)[H])=O)SC2)([H])N1[H]
InChi Code
InChI=1S/C16H29N5O3S/c17-21-14(23)8-2-1-5-9-18-13(22)7-4-3-6-12-15-11(10-25-12)19-16(24)20-15/h11-12,15H,1-10,17H2,(H,18,22)(H,21,23)(H2,19,20,24)/t11-,12-,15-/m0/s1
InChi Key
IJJWOSAXNHWBPR-HUBLWGQQSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Biotin LC hydrazide is a reactive probe that is used to biotinylate carboxyl or vicinal hydroxyl groups on carbohydrates, glycoproteins, or other glycoconjugates.1 It can also be used to link biotin to antibodies and ribonucleotides.1,2 Biotin LC hydrazide contains a long spacer arm to prevent steric hindrances.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Diamandis, E.P., and Christopoulos, T.K. The biotin-(strept)avidin system: Principles and applications in biotechnology. Clin. Chem. 37(5), 625-636 (1991).

    2. Haugland, R.P., and You, W.W. Coupling of antibodies with biotin. Methods Mol. Biol. 418, 13-23 (2008).