A cephalosporin antibiotic
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Cefdinir

Item No. 21521

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(6R,7R)-7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(hydroxyimino)acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CAS Number
91832-40-5
Synonyms
  • BMY 28488
  • CI-983
  • FK-482
Molecular Formula
C14H13N5O5S2
Formula Weight
395.4
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 0.3 mg/mLDMSO: 2.5 mg/mLPBS (pH 7.2): 1.25 mg/mL
λmax
224, 288 nm
SMILES
C=CC1=C(C(O)=O)N2[C@]([C@H](NC(/C(C3=CSC(N)=N3)=N\O)=O)C2=O)([H])SC1
InChi Code
InChI=1S/C14H13N5O5S2/c1-2-5-3-25-12-8(11(21)19(12)9(5)13(22)23)17-10(20)7(18-24)6-4-26-14(15)16-6/h2,4,8,12,24H,1,3H2,(H2,15,16)(H,17,20)(H,22,23)/b18-7-/t8-,12-/m1/s1
InChi Key
RTXOFQZKPXMALH-GHXIOONMSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 mg

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    Cayman Chemical
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    Product Description

    Cefdinir is a cephalosporin antibiotic.1 It is active against numerous Gram-positive and Gram-negative bacteria, including β-lactamase-producing E. coli, K. oxytoca, K. pneumoniae, and P. aeruginosa clinical isolates (MICs = 0.25-16 µg/ml). Cefdinir is protective against sepsis induced by strains of S. aureus or H. influenzae in mice with 50% protective dose (PD50) values of 2.7-35 and 3.1-5.8 mg/kg, respectively.2 Formulations containing cefdinir have been used in the treatment of Gram-positive and Gram-negative infections.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Briggs, B.M., Jones, R.N., Erwin, M.E., et al. In vitro activity evaluations of cefdinir (FK482, CI-983, and PD134393). A novel orally administered cephalosporin. Diagn. Microbiol. Infect. Dis. 14(5), 425-434 (1991).

    2. Cohen, M.A., Wold, S.A., Meservey, M.A., et al. In vivo therapeutic efficacy of cefdinir (FK482), a new oral cephalosporin, against Staphylococcus aureus and Haemophilus influenzae in mouse infection models. Diagn. Microbiol. Infect. Dis. 18(1), 41-47 (1994).